Recent Articles
Constructing RNA Chains Through Transcription in Virology

Constructing RNA Chains Through Transcription in Virology...

Written by: The Midland Certified Reagent Company Summary: Learn more about RNA polymers, an important part of all life on Earth. The RNA polymerase (RNAP) enzyme is essential to organic life. Discovered in the 1960s, RNA polymers produce primary transcript RNA, are found in many viruses, and polymerize ribonucleotides at the 3’ end of an RNA transcript. If the encoded gene is a protein, messenger RNA (mRNA) can act as a template for the protein’s synthesis. In virology, positive strands of RNA viruses contain the necessary genetic information for viral replication, or the production of many new infectious particles in a brief period of time. The RNAP enzyme is present in every single viral particle. RNA polymers are complex, but the enzyme’s activity can be viewed on an electron-micrograph and tracked from the very beginning of transcription at the 3’ end, to the conclusion, at the 5’ end, at which point the RNA molecules have been completely transcribed. The DNA polymers must first assemble nucleotides into DNA molecules. Then, in the first stage of gene expression, a DNA sequence is read and copied into a complementary primary transcript RNA strand. While most viruses’ RNA synthesis is initiated by DNA-dependent RNAPs, other positive-strand viruses, such as influenza and polio, rely on RNA-dependent RNAPs instead. As the latter is never found naturally in mammalian cells, it is highly invasive, but can fortunately be targeted and inhibited by antiviral compounds. Viral replication...
What are the Costs of Researching Cures?

What are the Costs of Researching Cures?...

Written by: The Midland Certified Reagent Company Summary: Utilizing automated means, medical engineers can manufacture strands used in DNA or RNA synthesis. The process of researching the cure for a disease used to be more expensive than it is today. That’s because entire DNA molecules, rather than just strands, were manufactured and used for testing. This was highly inefficient. Most reactions need only a segment of DNA for synthesis. Since the 1970s, medical engineers have utilized automated machinery to create and replicate DNA segments. How Many Base Pairs for $1? Right now, the answer is probably somewhere between one and three base pairs. That’s because the cost for reading genomes is much higher than the cost of writing genomes, but the cost can lower raise depending on how many base pairs one needs to manufacture. As the tally goes higher, so too does the price. Companies that manufacture oligos for RNA synthesis also have a limit to what they will guarantee. If you needed 600 base pairs for a project, you might not be able to acquire it so easily. This is because they will typically stitch smaller pieces together, as opposed to performing the extra sequencing. There are also fees depending on what you want, exactly, out of siRNA. If you needed a higher concentration, for example, your costs would raise or lower accordingly. The good news is that the costs of DNA sequencing are stabilizing, if not...
Three Ways Your Vitamix Blender Will Improve Health

Three Ways Your Vitamix Blender Will Improve Health...

 Three Ways Your Vitamix Blender Will Improve Health A good blender can do wonders for your health, especially if you get involved in the practice known as “juicing.” This term had a negative new wave connotation, but it’s much easier and more accessible today. Juicing is healthy, popular and fun. You’ll up the intake of veggies, improve your energy throughout the day and feel refreshed and ready to go. Detox Diet You’ve probably heard both sides of the detox debate, here are the facts. Your body does cleanse itself, but a detox done responsibly is one of the best ways to help this cleansing process. Good dieticians will specifically tell you not to over cleanse, and to be mindful of the signals your body is sending to you. A blender detox can be healthy if you do it properly, and you’ll feel great after it’s over. Increased Veggie Intake Kale, spinach and other leafy greens aren’t typically in the average person’s diet. Blending them into delicious and healthy smoothie recipes helps mask the taste, and, more importantly, allows you to cram even more veggies into your diet. Even people with a steady vegetable intake would benefit from adding more into their diets. Reduce Calories the Healthy Way Too often, we cut calories the way we cut expenses. Unfortunately, our bodies don’t work like our wallets do. We don’t get healthier, necessarily by cutting. At least not recklessly. Reducing caloric...
Human trials with African mango

Human trials with African mango

Article written by Cellan. With the introduction of African mango to the West, interest is growing to find many benefits it offers. Trials that were limited to animals are now finding its way into humans. One recent article published on the Internet cites a study conducted by the University of Yaounde I using a double blind test on its impact on obesity. Group included 40 women ages from 19 to 55. Participants were given one of two capsules. Those who were selected to take African mango were given three capsules, three times a day, each time 30 minutes before the meal. The daily total amounted to 3.15 grams of African mango extract. The control group took 350 mg of oat bran three times a day. Participants were evaluated weekly for body weight, body fat, and waist and hip circumference. Additional information on appetite and gastrointestinal issues were also collected. The group that took African mango shown 39.21 percent decrease in total cholesterol, 44.9 percent reduction of triglycerides, and 45.58 percent reduction in “bad cholesterol.” This is why Cellan Diet Pills use African mango. Now researchers are conducting more and more human trials with African mango and preliminary results are encouraging. This is why Cellan Diet contains inner seeds of African...
A Chemical Approach to Sustainability

A Chemical Approach to Sustainability...

Written by: The Midland Certified Reagent Company Summary: Substances we use every day can be formed synthetically, reducing waste. Petroleum is one of the most taxing substances we as humans require, but it’s a major part of many synthetic goods we continue to rely on. There is a fear that if we continue production at these levels we risk running out of resources required to synthesize these goods. However, thanks to oligo synthesis, scientists are researching artificial ways to create the substances we need to survive. This means less waste and alternative uses for materials we thought had only a few applications. How it Works Every organism needs certain sugars to survive in its day to day life. It gets these sugars through arious means, consumption being a big one for humans, and those sugars are processed in such a way as to perform certain tasks. There are many organisms that process sugar with a carbon bi-product. If we were able to somehow reconfigure these reactions, we could use ethanol to make nylon. Taken to the extreme, the very air you breathe, with everything carried inside of it, can be re-synthesized to create whatever we need. One can conceive particulates reformed into dry wall siding or carpeting. Literally plucked, as it were, from thin air. The Role of Synthesis Any advancement is going to rely on specific reactions, which means DNA synthesis is required to manipulate genetic structures. Custom...
Lose body fat with African mango and green tea

Lose body fat with African mango and green tea...

Article written by Cellan. Fats are a larger group of compounds known as fatty acids. Some fats are an essential nutrient of our diet and it comes in many forms. Having more than we need to function and the wrong kind causes far too many problems including obesity, higher cholesterol, and high blood pressure. Since fat makes our food testier, we use fat in everything. But the recommendation is to limit no more than 30 percent of calories from fat. Saturated fat increases the low-density lipoprotein (LDL), commonly called as “bad” cholesterol. Unsaturated fat becomes liquid under room temperature and found in many vegetable oils, nuts, fish and other natural products. It is high in calories but do not raise the LDL level. Shortening and hydrogenated vegetable oils contain Transfat and increases the LDL level. There are many ways to control various fats in our body including diet, medication, supplement, exercises and many other ways. A supplement such as Cellan Diet made of all natural ingredients can help to control fat content in your body. African mango and green tea are two main natural products that has been proven to lower body fats. This is why Cellan Diet Pills contains...
Health Tips
Checking In on the Vibes You Are Sending Out... Written by Dr. Eric Amidi. We all know that the main objective when following the Law of Attraction is to send out the right sort of vibes to the Universe. These are the types of vibes that serve as a signal that you are in a positive and abundant frame of mind and are ready to receive abundance in return. Unfortunately, it’s difficult to tell exactly what sort of vibes you are sending out. It isn’t something you can see or test for, but sending out negative vibes can...
Relaxation and weight loss effects of green tea... Guest post is provided by Cellan Pills. Theanine and EGCG rich green tea helps to bring calm and shed few pounds off your weight. This is why Cellan Diet contains 100 percent green tea extract, Vitamins and others to provide calming effect and lose weight. Have you sipped a calming cup of green tea lately? If so you will know how it helps you to relax. This calming effect is due to a substance contained in green tea known as theanine. Belonging to the amino acid family, theanine is...
Problem: Migraines, neck stiffness, vertigo... Solution: Blue sapphire orthotic Background: Jen had been a dental assistant for a number of years. Her teeth were worn down in the back of her mouth, so the dentist at her office offered to fix them. She had a background in dentistry and trusted the dentist, so they decided to alter her posterior chewing teeth. Her dentist tried to increase the vertical dimension of her bite by increasing the size of the rear molars, but Jen didn’t feel right. The dentist made the corrections a few teeth at...
Random Articles
5 Habits to Prevent Alzheimer’s Disease... A recent study reveals that you can prevent Alzheimer’s Disease among a host of other neurological disorders, according to data compiled by almost 16 researchers. And it’s almost by 70% to 80%, according to Neal Barnard, president of the Physicians Committee for Responsible Medicine. So, here are 5 habits that will help you stave off Alzheimer’s Disease: #1: Reduce the intake of trans and saturated fats Bad fats, such as trans and saturated fats, tend to increase cholesterol, which, in turn, increases the production of the beta-amyloid plaques in...
Chiropractors can help with your knee problems... An experienced chiropractor knows from experience that knee problems can cause extreme pain and can many time be debilitating. There are many reasons why people experience knee pain. And, it’s important to be aware that everyone, at any age, is at risk. A fall, an auto accident, a sports injury, or some other acute, traumatic event can cause knee pain. Nonetheless, the knee problems that most people experience, especially as they get older, are viewed as “non-trauma knee problems.” In other words, most knee problems are not due to...
Better Massages Begin with Better Tables... Written by Comfort Soul Whether you run a salon yourself or you simply enjoy relaxing in the privacy of your own home, a good massage is essential. However, there are a number of elements that go into creating one far above the person who provides it. You need the right oils and other treatments, for one thing. The right atmosphere is extremely important where relaxation is concerned too. You also need to make sure you’re using the right furniture. Every good masseuse knows they’re only as good as their massage...